Penicillin skin test negative also to allergy

China's traditional Chinese medicine reported

        As is known to all, the injection of penicillin skin test must be done before. But because of the individual difference, even if the normal skin test, also can't completely put an end to penicillin allergies. Because penicillin can appear sometimes slow response, a skin test negative, a start injection no discomfort, but after the injections for a few days in allergic reaction, it is called on medicine in serum disease reaction type. In general after 3 ~ 12 days occur, clinical manifestation visible fever, joint swelling and pain, itchy skin, and urticaria, whole body lymph node enlargement, abdominal pain, etc.

        Penicillin allergic reactions varied, serious may smell smell of penicillin, would immediately had rashes, shock and allergic reaction; And some people may need several hours or even days after only after local skin rashes happened with minor delay sexual allergic reaction. In addition, when the skin test penicillin dose concentration small, slow to respond to a person at that time may be on the negative, but in the process of infusion, along with the dose concentration is more and more big, can produce allergic reaction. In addition, and the transfusion during or after infusion, some people may be the product of metabolic generation to penicillin allergies, this could also lead to penicillin delayed allergic reaction. To reduce allergic reaction, in the use of penicillin should notice the following several aspects when the question:

        1. Don't in patients under the condition of the very hungry muscle injection or intravenous injection of penicillin. An empty stomach will reduce the body to use tolerability, not only easy appear allergic reaction, and prone to "YunZhen" phenomenon.

        2. No matter muscle note or intravenous infusion, for the first time the dosage shoulds not be too big, should start from the dose and no adverse then gradually added amount.

        4. The first muscle injection when had better not take stance, should take a seat or lie down, the injection, patient should stay 10 to 20 minutes, without feeling unwell, then left. Injection process like a dizzy, bosom frowsty, sweat buildup, etc., shall inform the medical staff.

        5. Intravenous injection of penicillin, started speed is not too fast, every minute should not be more than 40 drops, observation 10 to 20 minutes, if no adverse reaction, to pick up speed. In the process of infusion, if appear facial, limbs, torso, skin rash, itching, or appear bosom frowsty, abnormal breathing difficulties, shall be immediately told the doctor.

        6. Intravenous injection of penicillin, concentration not too high, children will take into consideration the according to weight reduction.

        In addition, because penicillin in plasma of half-life for 30 to 60 minutes, so, the best solution in one hour after drops. (ZhuJianCai)