Twenty HaYiDa a joint study found

Crucifer helps control pancreatic cancer

Our reporter correspondent QiuLi YiXiaoFeng

China's traditional Chinese medicine to

        "Cruciferae vegetables extracted a nutrients - dimerization indole, can promote pancreatic cancer cell differentiation, and displays the unique anticancer activities." Recently, HaYiDa attached by twenty digestive tumor medical lauffer jm associate professor with the MD Anderson cancer center expert cooperation completed a research topic, for people use natural plant of the effective components of pancreatic cancer prevention and control provides an important theoretical basis.

        Cruciferae vegetables mainly include Chinese cabbage category, brassica, mustard class and radish vegetable crops, etc. Epidemiological studies show that cruciferae vegetables can reduce the risk of some cancers, such as lung cancer, colon cancer, breast cancer, etc. The anticancer effect the most prominent are broccoli (LuCaiHua), turnip, cabbage, cabbage. Cruciferae vegetables can cancer prevention and fighting against cancer, because contain phytochemicals - isothiocyanate and indole, etc., but for the exact mechanism of cognitive science still lack.

        In January 2011, lauffer jm doctor to American Houston MD Anderson cancer center digestive laboratory do postdoctoral research work. In the world's top cancer diagnosis and treatment center, he and his colleagues cooperation, will crucifer natural chemical composition dimerization indoles and pancreatic cancer cell mixed cultivating, found that the former could significantly inhibit the growth of the latter, and the dose dependence, At the same time promote pancreatic cancer cells from high malignant degree to lower malignant degree of cell differentiation, adjust related differentiation and the expression of molecular markers pancreatic cancer stem cells. The study also found that, in the dimerization indole anti-tumor growth and to promote cancer cell differentiation process, a gene called KLF4 material have "switch" kind of regulation and control function. The results lock the dimerization indole anti-cancer channel of the key targets for dimer indole prevention and treatment of pancreatic cancer occurrence, development found the exact scientific basis.

        At present, pancreatic cancer was regarded as the king of carcinoma, once the patient into the middle-late, survival time is very short, prognosis is extremely dangerous. And the scientific research results suggest that, as cruciferous extract - dimerization indole not only can inhibit tumor occurs, to promote cancer cell to normal cells direction differentiation, and further clarify the nutrients through the regulation of gene expression, and then contained pancreatic cancer to life ruthless "encroach on". If people can effectively and reasonably make use of these natural biological composition, is expected to reduce the incidence of pancreatic cancer. If can for key targets developed the related regulation drugs, will be for the treatment of pancreatic cancer brings new dawn.