Long squat legs hemp from ischemia-reperfusion injury

The fourth military medical university pathology and pathophysiology teaching and research section WangRuiAn

Sources: health

        This is an almost everyone had experience: night sleep, or long after crouching to stand, often have legs hemp feeling.

        A seemingly simple question, but few students can give a correct answer. Even if is a doctor and university teachers, may also have a lot of misunderstandings. Most people will think, this is because the nerve compression's sake. On the Internet, there is a "squat down for a long time, leg why pins and needles" anime. Interpreted as, legs have very rich in blood vessels and nerves, long squat, blood vessels are oppressed, nerve not nutrition, so pins and needles. It sounds quite reasonable, but think carefully just found out the problem. Nerve compression or vascular compression, the nerve not nutrition, should be squat time hemp, after standing is good. But in fact who all know, legs pins and needles in changes in body position happened after. Moreover, the legs move, the hemp badly. Go to bed at night, too, side leg pressure, commutation position hind leg began to hemp. Stretch your legs, activities activities, the activities the hemp, but after a while will automatically disappear. Nerve compression or nerve not nutrition say, is not enough to explain.

        In fact, this is because the blood vessels for a long time after compression, the organization to get blood perfusion damage caused by the reaction, called ischemia-reperfusion injury in clinical medicine, have very important significance. For example, patients after myocardial infarction, emergency do artery catheter intubation RongShuanShu will remove blood clots. After the termination of the embolism several minutes, because the heart after ischemia reperfusion injury may lead to produce myocardial arrhythmia, even endanger life, so, in thrombolysis before you do your antiarrhythmic preparation. This repeated perfusion damage happened mechanism and leg mechanism of pins and needles is same, only is currently can not be said clearly.

        Organ ischemia-reperfusion injury also in cerebral thrombosis (stroke) RongShuanShu, heart, liver, kidney, intestine and organ grafts on blood perfusion began, and replantation of severed limb, etc. There is no doubt that study this tissue damage emergence mechanism and effective prevention and control has important clinical significance.