Life take precautions against "food medicine phase grams"

Central south university xiangya 2nd hospital nutrition division chief physician TangDaHan

Sources: health

        As is known to all, oral drug and food nutrients are through the human digestive tract intake, digestion, absorption into the human body, they in the body metabolism and discharge process is also dependent on the same organs and ways, so food (nutrients) and drug inevitably occur influence each other. We call this kind of influence for food and drug interactions (FDI).

        Some nutrients can affect drug absorption

        Food and nutrients to the effects of the drug are various, for the physical and chemical properties of different drugs, the food and the body physiological condition also have different effect, so that the drug absorption, distribution, metabolism, discharge in different degree of change. FDI mechanism including affect drug absorption, such as iron rich foods such as liver, blood, red meat, such as black fungus can make erythromycin absorption decreased by 47% ~ 60%, iron and tannins (such as green tea) can reduce the alkaloids drugs (such as reserpine, ephedrine, etc.) absorption.

        Grapefruit juice can make the lower blood pressure

        In addition, FDI effects of drug metabolism, such as protein, vitamin and mineral nutrition level shortage will affect drug enzyme synthesis, leading to enzyme activity fell, the normal metabolism of drugs by interference, so as to influence effect; At the same time because of the human body for drug clearance rate is reduced, increased drug toxicity. A kind of grapefruit juice called furan coumarin material by inhibiting the activity of the enzyme cytochrome CYP3A4 with felodipine (antihypertensive drug metabolism and as a result, patients occur hypotension.

        Food and drug interactions can also affect drug discharge, the influence of acid and alkaline urine diet can affect some drug discharge rate, thereby enhancing efficacy or adverse reactions. Such as taking basic drug quinidine when eat orange, drink grape juice and basic food and at the same time take antacids, but because of urine alkalify inhibition quinidine discharge and cause poisoning.

        Eat some medicine before and after don't eat cheese

        Contain vitamin K rich animal liver, broccoli, spinach, broccoli, bud Swiss chard, cilantro and China are faring direct antagonistic action and influence the anticoagulant effect. Rich in histidine food (fish, cheese, meat products, etc.) in the body can be transformed into histamine, decrease antihistamines chlorpheniramine, diphenhydramine, promethazine, etc, and the role of histamine induced by accumulation, dizziness, headache, such as palpitate symptoms.

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