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2013年09月29日
Secondary development
Source: quanzhou evening news (quanzhou)
Nearly 100 years of modern medical practice to make people gradually realize that the modern western medicine for the treatment of acute disease has a good effect, and for such as diabetes, cancer and type age degenerative disease of metabolic disease characterized by but there are some limitations. Characterized by theory of compatibility of traditional Chinese medicine using multicomponent the use of a combination of targets for drugs, for these diseases might have better curative effect.
Especially in Europe and Japan in the world, since the turn of the century, the study of traditional Chinese medicine (TCM) and the use of gradually on the rise trend, formed a "for the" phenomenon. Again good for traditional Chinese medicine prescription development and transformation, will become the focus in the current and future a period of time.
National "twelfth five-year" science and technology plan clearly put forward again, in the next five years to focus on support and in around 30 varieties of traditional Chinese medicine (TCM) of secondary development, the second development for Chinese medicine industrialization, provide a good atmosphere of policy support.
At present, all over the country have invested a lot of scientific research strength, will the good recipe in pharmacopoeia according to the theory of modern medicine method for quadratic transformation and development, made great achievements, especially the application of the new preparation process, adopted a new Chinese medicine formulations, changed the traditional dosage forms the shortcoming of poor taste, such as compound danshen dropping pill, ageratum upright soft capsule, wuji baifeng pills and liuwei dihuang pill, secondary development of traditional Chinese medicine (TCM) has achieved great success, received good social benefits and economic benefits. According to statistics, in 2010 in tianjin alone, in traditional Chinese medicine (TCM) secondary development, driven by its sales over one hundred million yuan to reach nine varieties of traditional Chinese medicines.
It is important to note that not only at home, also gradually rise on the international an upsurge of Chinese traditional medicine research and development of secondary, there are a number of international business studies in accordingly. Such as sales in the domestic market of Germany and France JiuXinDan of ginkgo leaf preparation, Japan, and BaoXinAn oil, wind to oil, safflower oil, etc., are all secondary research and development of "derivative". These drugs prescription mainly comes from Chinese ancient famous doctor square generic, about 75% in raw material by the output in our country, in a foreign country sells back our country, after the research and development of the secondary processing and win a high profits. At present, both at home and abroad will be Chinese traditional medicine development of secondary industry, as one of the important new growth point of new drug development.
In the treatment of cancer, the combination of systems biology based medicine is gradually rise, its research and development train of thought is essentially from traditional Chinese medicine theory as the basis, compatibility with the common functions of combination drug as the goal, to develop new clinical effective drugs. Clinical use show that some characteristics of compound prescriptions for tumor growth and regeneration after the surgery has obvious inhibition and longer effect.
Though restricted by various factors, is clear about in the traditional Chinese medicine with the chemical composition of antitumor activity is still the bottleneck of restricting Chinese medicine modernization, but with the great progress of modern physics technology and its application in the biological medicine industry, this problem has made great improvement.
Gradually to the modern Chinese medicine research at the molecular level, modern molecular biology, cell biology, genomics, proteomics research means, a variety of disciplines such as not only to explore the effect of traditional Chinese medicine integrity, multiple targets and complexity has made an important contribution, but also to expand the medicine source, new with old drug.
Liu Qingsong
Liu Qingsong, researcher, Chinese academy of sciences, life science, deputy director of the center for science in the strong magnetic field magnetic resonance (NMR). Mainly engaged in kinase and epigenetic targets as the research object of the development of antitumor drugs, as well as the related tumor drug resistance mechanism of medical research.