Development of traditional Chinese medicine: need more "must belong to it" 
 
 
Release date: 2014-09-24
 
 
Source: journal of science and technology
 
 
Author: anonymous 

        "So far, our country new drugs of traditional Chinese medicines produced only two internationally recognized" become the 14th national Chinese medicine and natural medicine academic seminar, experts were mentioned most of a word. China institute of traditional Chinese medicine academy of sciences, director of the center for drug safety evaluation, the lead researcher, said the reactions every year in China research and development of traditional Chinese medicine new medicine quantity as many as dozens or even hundreds of, but the real in the treatment of a disease to "away from the medicine did not" this level of new drug of Chinese medicine, only artemisinin and arsenic trioxide both. 
 
        The reactions that, nearly 30 years, China's research and development new drugs of traditional Chinese medicines listed not only quantity, but also a located in the forefront of new drugs in the clinical medicine phalanx, are like the flower, antipyretic capsule, compound danshen dropping pill and thrombosis through injection of a batch of new drugs of traditional Chinese medicines "have an advantage and characteristic", but our country still lack of new drug of TCM "take out" and lead to a "buzz" medicine of innovation at home and abroad. The so-called "take out" and "sensation", is this kind of medicine in clinical disease first-line drug treatment is "must belong to it," rather than a dispensable. He cites an example. In 2011 in the biomedical field won the famous awards the lasker award, the prize is not the artemisinin and other antimalarial drug developers take the initiative to apply for, but the third party recommendation, the medicine caused a sensation in China. The committee believes that because of artemisinin, millions of children's lives are saved. 
 
        China is a natural product research power, 40% of natural products chemistry paper from China in the world, an annual increase of more than 4000 kinds of new natural products, found that a large number of active ingredients. 
 
        However "active range and new drug". Second military medical university, professor zhang wd think target discovery and optimization of new drug of TCM research is not enough, not enough research into into medicinal, is the active ingredient is not enough to be the main cause of clinical first-line drugs. 
 
        "Basic research is one of the innovation is an important source of medicine research and development." Reactions that all the generation of new drugs and the progress of basic research and new knowledge of the master, "from the main body of returnees, the declaration of the base drug companies first found new ER36 estrogen receptor in basic research, and found that the receptor and some correlation between tumor occurrence and development, on the basis of the screening and research and development to Chinese medicine treatment of liver cancer drugs, the drug is expected to recently completed clinical study by the agency." 
 
        "The name old doctor of traditional Chinese medicine clinical experience combined with the modern medicine, sublimation become perfect innovative new drugs, this is our new drug research and development advantages, and 'take shots' new drugs produced by important way." The reactions with famous ophthalmology of traditional Chinese medicine experts developed by combined with medicine expert professor tang eye drops of new drug of TCM, for example, illustrate the importance of the combination of the two above, according to his many years of clinical experience in the research and development of tang by the eye drops a treatment for eye diseases, but the eye drops is shorter. Experts will eye drops of preparations of Chinese medicine preparation into drops of ophthalmic gel agent, prolong the effect of the drug, so as to improve the old Chinese medicine eye drops. 
 
        With only two new drugs can get you anything embarrassing situation, zhang wd, "most modern traditional Chinese medicine has no specific molecular targets, mechanism of action is not clear, are mostly in some partly verified the therapeutic effect on the disease animal model, from the level of research and development on hard to accepted by international medical mainstream academia and industry." 
 
        Reactions, at the same time of strengthening basic research, should pay attention to save name old doctor of traditional Chinese medicine treatment experience, thought and the experience of in TCM theory and make it combined with modern medicine and pharmaceutical theory, developed a more characteristic and more effective new drugs of traditional Chinese medicines of Chinese medicine, so as to benefit the world, to the benefit of mankind. 
 
        He also suggested that strengthen clinical hospital of traditional Chinese medicine clinical practice with scientific sex, found in the treatment, optimization, evaluation, finally Chinese medicine new drug research and development.