Please avoid alcohol and tobacco

2017-03-14

Source: Health News

  
      Drinking

      The main ingredient of alcohol is ethanol, and ethanol is an inducer of many metabolic enzymes, drinking will accelerate the removal of some drugs in the body, such as phenobarbital, phenytoin, analgin, warfarin and so on. Drug metabolism to speed up, stay in the body shortened, lower efficacy.

      Long-term large number of alcohol, but also cause different degrees of liver damage, and even lead to drug poisoning. Antihypertensive drugs such as nifedipine (heartache), if the same service with wine or medication during drinking, it is easy to cause low blood pressure. Alcohol can also enhance the hypoglycemic effect of insulin. Such as hypoglycemic agents such as paracetamol (hypoglycemic), glibenclamide (glibenclamide), insulin, etc., can cause hypoglycemic shock, and can induce lactic acidosis.

      After drinking, the digestive tract blood vessels will expand, increase the absorption of drugs, which lead to adverse reactions. Aspirin and salicylic acid drugs themselves have damage to the gastric mucosa caused by gastric ulcer side effects, such as with the wine with the service, can induce ulcers, causing acute hemorrhagic gastritis. Taking metronidazole, furazolidone, tinidazole, cefoperazone during drinking, will occur disulfide-like reaction, the patient showed facial flushing, tachycardia, nausea, vomiting, abdominal pain, headache and so on. This is because the above drugs can inhibit the decomposition of ethanol, so that the metabolic process of intermediate - acetaldehyde degradation blocked, resulting in acetaldehyde accumulation in the blood, increased concentration caused by ethanol poisoning. Therefore, taking these drugs during the period or withdrawal within two weeks should not drink.

      In addition, alcohol can also increase the stability of hypnotic drugs on the central nervous system inhibition, taking these drugs when drinking, can lead to poisoning, respiratory depression, and even death. In short, regular drinkers should be two days before the medication forbidden wine, withdrawal five to two weeks before drinking again.

      Smoking

      Smoking has an effect on the efficacy of many drugs, but also increase adverse drug reactions, because the polycyclic aromatic hydrocarbons in tobacco is a strong liver enzyme inducer, can accelerate the metabolism of drugs.

      Smokers taking antipyretic analgesics (to pain tablets) effect was significantly reduced, and some efficacy is only non-smokers l / 10. Smoking can also delay the emptying of food in the stomach, such as antacids cimetidine, ranitidine, famotidine, etc., for the treatment of gastric, duodenal ulcers and upper gastrointestinal bleeding, often Due to smoking to vasoconstriction, delayed gastric emptying time, slow down the absorption rate of drugs in the small intestine, leading to stomach, duodenal ulcer healing slowed down. Tobacco nicotine (nicotine) on the central nervous nerve excitement, against diazepam, chlordiazepam and other sleeping pills sedative hypnotic effect. Long-term large number of smokers, can be formed in the tracheal intima a layer of tobacco tar, the impact of asthma drugs aerosol, nitroglycerin aerosol absorption in the trachea, so that efficacy is reduced.

      Drink tea

      The tannins contained in tea can interact with protein, alkaloid or heavy metal salts and affect the efficacy. Various digestive drugs, such as multi-enzyme tablets, trypsin, yeast, milk enzymes and other protein-containing drugs, tannins and protein binding, the formation of tannic acid protein, to help digestion weakened, or even failure. Serving digitalis, digoxin and other cardiac drugs, such as with the same service with tea, will produce insoluble precipitate and hinder its absorption, so that drug failure. Metal ions containing drugs, such as iron, calcium, cobalt, bismuth, aluminum and other tea should not be the same service, or tannins and such metal ions produce precipitation, almost not absorbed by the body.

      Tea contains caffeine as a central stimulant, and sedative hypnotics stability, phenobarbital equivalent service, will reduce the role of these drugs. Caffeine can also stimulate the secretion of gastric acid, resulting in acid-suppressing drugs such as compound aluminum hydroxide, compound aluminum acid secret effect weakened. Many traditional Chinese medicine contains alkaloids, easy and acidic ingredients to produce precipitation, so that the effect of drugs reduced, so the service is not available when the tea delivery service.