Improve post-stroke depression to find a better way

2017-03-24

Source: Health News

     (Department of Neurology and Clinical Psychology, Beijing Tiantan Hospital Affiliated to Capital Medical University, National Center for Neurological Diseases, Beijing Institute of Brain and Cerebrovascular Diseases, Institute of Stroke, Beijing Institute of Critical Care A recent study by the laboratory showed that the use of cognitive behavioral therapy combined with antidepressants in patients with poststroke depression (PSD) was significantly more likely to reduce depression scores in patients with PSD than antidepressants alone, Recovery of motor function. Related papers recently published in the national science and technology core journals "Chinese Journal of stroke" on.

     Researchers searched 132 published articles on cognitive behavioral therapy combined with antidepressants in the treatment of PSD patients (9 of 111 articles, 21 in English), and 9 (584 patients) were eligible for Chinese mental disorders Classification and diagnostic criteria of randomized controlled trials into the research topic. (4 weeks, 8 weeks, 12 weeks, 21 weeks, 52 weeks) were divided into five groups based on the time of intervention and the different studies evaluated Hamilton (analysis of two groups of depression scale improvement and neurological recovery) Subgroups were analyzed. The intervention group was treated with conventional antidepressant drugs combined with cognitive behavioral therapy, while the control group was treated with traditional single antidepressant drugs. The overall analysis showed that the cognitive behavior intervention group was more effective than the control group to reduce the depression score. Among them, seven studies evaluated short-term effects of continuous interventions for PSD patients for 4 weeks, and five studies evaluated the effect of 8 weeks of continuous intervention. Two studies evaluated the long-term effects of 12 weeks, 21 weeks, and 52 weeks of continuous intervention. The results showed that, regardless of early intervention, or long-term intervention, intervention group depression rehabilitation effect is better than the control group.

     According to Professor Wang Chunxue, head of the project, PSD is a serious complication that occurs after various types of stroke, which can lead to an increased risk of cardiovascular and cerebrovascular events in stroke patients. It is an independent risk factor affecting the recovery of patients' Previous studies on PSD. In recent years, the study found that the disease is closely related to neurobiology and psychosocial factors, the patient will be post-stroke sensory motor disorders, cognitive and behavioral damage attributed to stroke, misunderstanding and low self-evaluation lead The occurrence of PSD.

      Wang Chunxue said that cognitive behavior intervention is mainly based on the theory of cognitive and behavior hypothesis, by changing the concept, thinking and behavioral methods to help patients understand the disease, improve bad cognitive, overcome psychological problems, and learn to control the emotional Short course of psychotherapy. Studies have shown that cognitive behavioral therapy is currently the only promising treatment for drug-resistant patients, combined with antidepressant drugs play a more therapeutic role, which can reduce the recurrence of stroke and prevent the recurrence of depression.