Recently, in the traditional Chinese medicine institute of China association for science and technology of 61 new ideas and theories academic salon "on, experts in the period of the medicine and transformation of medical discuss contact, think--

Transformation of traditional Chinese medicine scientific research development opportunity to medicine

Our correspondent TanXin

China's traditional Chinese medicine reported

        Transformation in recent years as a medical a new kind of medical research mode, emphasize the laboratory and clinical research two-way transformation between, strengthen basic research and clinical medical effective contact, the goal is to speed up the basic research achievements to develop new clinical diagnosis and treatment technology and the transformation of drug development. China's traditional Chinese medicine academy of sciences researcher song JianNa think: "the rise of the translational medicine and the clinic as basis, the traditional Chinese medicine with personalized treatment research provides a good opportunity of development."

        The laboratory and clinical research two-way transformation between

        Song JianNa introduces, at present transformation of Chinese medicine research must be combined with clinical development, clinical patients as the research object, in view of the syndrome differentiation classification, therapeutic principle therapies and formulas, syndrome, changes the effect assessment, and other key link; The literature mining start to question and hypothesis, widely absorption and application interdisciplinary, made up of the army.

        In recent years, a new kind of medical research mode, emphasize the laboratory and clinical research two-way transformation between, strengthen basic research and clinical medical effective contact. Through interdisciplinary, cross departments jointly mainly cross-disciplinary research is traditional Chinese medicine research made great achievements in the key and successful experience. Therefore need to introduction of systems biology research methods, use all sorts of group learning technology and develop different levels, and syndrome occurrence, development, classification and treatment effect assessment formulae and the sensitivity of the biological markers associated the screening of the group, and to give the viscera and the four diagnostic information positioning connotation of traditional Chinese medicine.

        And he would like to be able to have conditions in the institutions of higher learning, medical and scientific research institutions should speed up the form into the pace of traditional Chinese medicine (TCM) research center, the way to, a traditional Chinese medicine combined subject development across the department. He thought transformation can solve medical research has decades of traditional Chinese and western medicine "not problem.

        Ensure clinical treatment is safe and effective

        The Chinese academy of medical sciences researcher at the institute of medicinal plants SunXiaoBo said: "now of Chinese traditional medicine research is much more targets, research, for which no composition a compound around the clinical efficacy and background to study its activity or components. A lot of research is as long as found a composition, found a activity, that is the prescription of active ingredients, and from the clinical efficacy of the background. Some components of the research activity is out with clinical efficacy not related, or even in the opposite direction. Therefore, research must be around the clinical curative effect, the drug to the body to produce around effect.

        The second kind of research is the study of the Chinese medicine reducing, all is for the sake of the original theory expounded, right, the real development innovation is insufficient, can't touch, dare not to maintain. Research conclusion is often thousands of years or hundreds of years ago what is the best.

        We should introspect: what is found that some components, found that some dosage forms, made some targets, or how to through the research provides evolution, expounds the mechanism, raise the standard, ultimately ensure clinical is safe and effective, is our fundamental purpose of traditional Chinese medicine research.

        YiJiaoYan attention in effective combination

        Traditional Chinese medicine and transformation of the combination of the medical model, main is to speak from some of the traditional Chinese medicine and clinical information, through the method of dialectics, summed up in the academic thought clinical experience, and then combined with our basic research and clinical trials, explore the inner laws, eventually forming results, feedback to clinical services to the society.

        To this, Shanghai university of TCM hospital affiliated longhua YangYanPing introduced that the longhua hospital medicine, teaching and research on the combination of production, through the achievements and achievements of the way to realize the industrialization promotion. Already has formed more than 160 hospital preparations and apply for the 12 new drug certificate, applied for the national patent of invention and items, published more than 4000 papers (including SCI has 43 articles), there are more than 100 of works. In addition, still formed the rule of cancer including the centralizer some treatment law, promoted the development of the theory of traditional Chinese medicine.

        Is the clinical basic research, now get the 98 state funding item, and through the name studio of traditional Chinese medicine, Chinese medicine hospitals to promote the inheritance and inheritance.

        In the transformation of Chinese medicine to insist on characteristics

        Song JianNa said: "in the transformation in medical research, Chinese medicine to insist on their own features don't shake. Emphasize theory and clinical, Chinese medicine and traditional Chinese medicine combined and people-oriented, pattern identification and treatment principle, and keep the whole, dynamic, and adjust the balance of the basic theory of TCM, features."

        "The overall and dynamic" in traditional Chinese medicine is the human body and disease, development of the basic understanding. Chinese medicine emphasizes harmony between man and nature, and pay special attention to mutual relationship, think the happening of the disease, the development has the very strong space-time dynamic characteristic; Emphasizes etiology with individual place time, space, environment and the state will vary. This and modern "the biological-psychology-society" medical model and the corresponding system biomedical concept consistent.

        And, "regulation and balance" TCM prevention and cure of diseases is the means and the target. Not only Chinese medicine treatment for pathogens, treated not diseases, but sick people, so is far more than "more targets" complex whole regulation. Regulation is the goal of the balance, the pursuit of space-time dynamic characteristics with the overall balance of Yin and Yang, in order to realize the Yin pingyang secret, Yin and Yang niv, achieve vital qi, evil shall not save in dry goal.

        Thus, we think of compound Chinese medicine's overall adjustment is the material basis of the superiority of TCM. TCM compound is to realize the overall adjustment effect as the goal of adjustment methods, the effect of TCM compound evaluation shall also to measure the overall effect. We must make great efforts to carry out "and the overall effect of the corresponding biological markers group of" as the core of the traditional Chinese medicine research overall effect of molecular studies with disease from different card, with different Angle certificate, felt more strong, the effect of specific better fit for the new series of individual therapy components preparations. Only in this way, can return to traditional Chinese medicine for natural drug molecule attributes and realize the innovation of the compatibility of molecular herbal drugs provide theoretical basis.

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        Transformation medicine is a branch of medical research, in basic research and trying to build between the clinical medical treatment more direct link. Now, the transformation in the importance of medical health industry upgrading and the definition of it and constantly changing. As in drug design and development process, the transformation of meaning is typical of medical research results will be transformed into a real actual provide the patients with the treatment method, emphasize from the lab to the bed of the connection, and this is usually called "from the experimental platform to the bed".