Shanghai medicine back to a national science and technology progress award

"Artificial musk development and industrialization projects" save 26 million head of musk deer

Source: the liberation of the net

In the 2016-01-12 s were

Author: Chen Xi shake

Liberation daily The liberation of net news (reporter Chen Xi shake) natural musk, very rare, the average killing of a male musk deer can only get a 3 g, it's 433 kinds of proprietary Chinese medicine dependence on raw materials, the composition of proprietary Chinese medicine prescription accounts for more than 11% of the national proprietary Chinese medicine prescription ". As musk endangered, natural musk face the danger of disappearing, to shake the "foundation" of many proprietary Chinese medicine.

After forty years of unremitting efforts, Shanghai pharmaceutical group Shanghai co., LTD and other units to work together to complete "artificial musk development and industrialization" project has won the first prize in national scientific and technological progress. Project and research the main efficacy in natural musk material alternatives, and overcome the large-scale production, to find "no musk fragrance also" solution.

Protect the ecological: "save" the 26 million head of musk deer

Less than 600000 head of musk deer, of our country's existing, assuming that half of them are male musk deer, even killed, or for less than 1 ton natural musk. Chen Junli Shanghai co., LTD., general manager, told reporters that at present our country musk demand for more than 15 tons, rely on to kill the traditional way of musk deer fragrant don't fill in the gap.

How to balance the people use demand and the ecological resources protection? Must cross a path! Project is one of the persons involved YanChongPing recalls, formed in 1975 by the Chinese academy of medical sciences institute of drug lead, shandong jinan institute of traditional Chinese medicine of traditional Chinese medicine factory and Shanghai to participate in the group, with "top secret" project to carry out the artificial musk.

YanChongPing said, equipment advanced, in the 70 s, talent shortage is used to study the natural musk is only a little. Project team going, just use trace method, comprehensive analysis and master the natural musk, chemical components, active substance, pharmacological effects, formulation principle of key information, to find and develop key medicinal substances in natural musk substitute - fang live, important raw material of musk ketone was synthesized and the sea can be.

In the end, the artificial musk compound prescription, comparison, pharmacological effects of artificial and natural musk, security is good. In 1987, the ministry of health approval for clinical research and confirmed on the basis of alternative, the ministry of health in 1994, artificial musk is a unique to China legal alternatives to a kind of natural drugs and drug ingredients.

According to calculation, artificial musk enabled, equivalent to less killed 26 million musk deer, not only strengthen the endangered rare traditional Chinese medicine resources protection and sustainable utilization, also improved the international image and reputation in the field of animal protection in China.

Benefits to the people: artificial musk cost down eighty percent

Artificial musk Chen Junli tells a reporter, since 1994 to establish a new drug for traditional Chinese medicine, has been applied to national 760 enterprises. Is still in production and sales of 433 kinds of proprietary Chinese medicine containing musk composition, there are 431 species has been completely replace the natural musk with artificial musk, replacement rate above 99%.

"The 99% rate of substitution, is not achieved overnight." YanChongPing said while artificial musk and passes through various aspects "achievement" outstanding authority, but came out, many "old mage" subject to long-term formation of the concept and habit, also hard to accept. After 20 years, with the musk increasingly scarce resources, artificial musk production process of continuous improvement, the effect is more and more withstood the test, now artificial musk pills has become nightfall, Ann palace bezoar pills, pills for Sue us, heart of musk, important material of Chinese medicines, such as a variety of national recognition.

At present, the cost of artificial musk is around one 5 that in natural musk or so, many people can use lower price to buy quality almost the same and even more stable musk drugs. The reporter learns from Shanghai pharma, using natural musk nightfall pill as raw materials, 100 grains of specification once sold into 45 yuan, and replaced with artificial musk, the price can be reduced by more than half or two thirds.

Traditional Chinese medicine (TCM) innovation: Shanghai sword refers to internationalization

It is important to note that "artificial musk development and industrialization" project was awarded first prize of national scientific and technological progress, is Chinese traditional medicine research and development strength in Shanghai for the first time to shine all over the country. In that one year ago, Shanghai chiatai qingchunbao pharmaceutical group involved in the complete "proprietary Chinese medicine secondary development system and core technology research and industrialization" projects won the national science and technology progress award in 2014.

"It is undeniable that the wide application of artificial musk, cannot leave the previous scientific studies, more from the late industrialization and improve quality standards, this is Shanghai long-term cultivation accumulation of advantages." Shanghai drug supervision bureau Yan Zujiang said the Shanghai traditional Chinese medicine research and development team in a long time to undertake artificial musk apis can I and II of the pilot project, sea and the sea, I and II synthesis of key industrial test project, successfully overcome the standardization production of traditional Chinese medicine industry, industrialization of artificial musk successful promotion has played a positive role.

Success in artificial musk, on the basis of Shanghai traditional Chinese medicine research and development power will set out again, focus on traditional Chinese medicine to promote to the world. Shanghai pharma, will continue to intensify the building of the source of traditional Chinese medicinal materials, innovative to the concept of "quality is the result of design" the introduction of Chinese herbal medicine planting, build from source of medicinal materials quality traceability system. It is understood that the project was "salvia miltiorrhiza seed seedlings quality standard" has ISO international standards, "danshen medicinal quality standard" proposal has also for the international organization for standardization technical committee (ISO/TC249) of traditional Chinese medicine. In the future, the tranditional Chinese medicine, not only will grab r&d and industrialization of highland, will occupy more standardized highlands, obtain more say in the world.