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Side of traditional Chinese medicine (51) qingrejiedu licorice

 

 

"Chinese pharmacopoeia" : licorice

Licorice medicine name 】 【

M: o "pinyin" G ā n C

[English] RADIX GLYCYRRHIZAE

【 origin 】 this product is a leguminous plant licorice Glycyrrhiza uralensis. He, swelling fruit licorice Glycyrrhiza inflata Bat, or light fruit licorice Glycyrrhiza glabra l. root dry. Spring and autumn season two excavation of, remove hair root and dry.

【 description 】 licorice root and cylindrical, 25 ~ 100 cm long, 0.6 3.5 cm in diameter. Different skin elastic. Surface red-brown or ash is brown, with significant vertical wrinkles, grooving, lenticels and sparse fine roots. Solid and cross section slightly fibrous, yellowish-white, powder, cambium ring, ray radiation, some have a crack. Rhizomes and cylindrical, the surface has bud mark, myelinated in central section. Micro, sweet and special taste.

Swelling fruit licorice root and rhizome stout wooden, some branches, skin coarse, dusty brown or beige. Qualitative hard, wood fiber, powder. Rhizome adventitious bud and more bulky.

Light fruit licorice root and rhizome quality of a material is solid, some branches, skin coarse, not much gray brown, lenticels fine but not obvious.

[identify] : (1) of this product this cork layer for sequence brown cells. The cortex is narrow. Phloem ray broad, bending, more often now fissure; Fiber bundle, the wood or micro wood, parenchyma cells often contain calcium oxalate Fang Jing around; Screen nest of tubes is often due to compression deformation. Beam in the cambium is obvious. Xylem ray wide 3 ~ 5 column cells; The catheter is more, to 160 microns in diam. Wood fiber bundle, parenchyma cells also contain calcium oxalate Fang Jing around. Root center without pulp; Root pulp in the center. Powder light tan. Fiber bundle, 8 ~ 14 microns in diameter, wall thickness, lignification, around parenchyma cells containing calcium oxalate Fang Jing, formation of crystal fiber. Calcium oxalate Fang Jing. Bordered pit catheter is bigger, rare reticulate vessel. Red brown cork cells, polygon, the wood.

(2) apply the powder 1 g, plus ether 40 ml, heating reflux for 1 hour, filtration, liquid to add 30 ml of methanol, heating reflux for 1 hour, filtration, the filtrate zhenggan residue 40 ml water to dissolve, with n-butyl alcohol extract 3 times, every time 20 ml, merger, n-butyl alcohol liquid water washing three times, zhenggan residue add methanol 5 ml to dissolve, as the test solution. Another take licorice control medicinal material 1 g, with the legal system into a controlled medicine solution. In ammonium glycyrrhetate reference substance, add methanol made each 1 ml contains 2 mg of solution, as a reference substance solution. According to the thin layer chromatography (appendix Ⅵ B) test, from the above three kinds of solution 1 ~ 2 mu l, each point in the same with 1% sodium hydroxide solution preparation of silica G thin layer plate, with ethyl acetate - formic acid, glacial acetic acid and water (15:1:1:2) as an agent, and taken out, dry spray with 10% ethanol solution of sulfuric acid in the 105 ℃ heating to the spot color is clear, can be examined under a uv lamp (365 nm). In the chromatogram of the test, chromatographic corresponding to the position, show the same color of the fluorescent spots; In the position of accordingly with reference substance chromatography, show the same orange fluorescent spots.

According to content determination 】 【 (appendix Ⅵ D) with high performance liquid chromatography (HPLC) method.

The chromatographic conditions and system suitability test With octadecyl silane bonded silica gel as the filling agent; Methanol - 0.2 mol/L - glacial acetic acid, ammonium acetate solution (67 - now) as mobile phase; Detection wavelength of 250 nm. Theoretical plate number calculated by ammonium glycyrrhetate single peak should be not less than 2000.

The preparation of the reference substance solution Take about 10 mg ammonium glycyrrhetate single reference substance, precision said, 50 ml volumetric flask, dissolved in mobile phase and diluting to scale, shake well, for a quick (each 1 ml contains ammonium glycyrrhetate single reference substance 0.2 mg, reduced glycyrrhizic acid 0.1959 mg).

Powder in the preparation of test sample solution for this product is about 0.3 g, precision said, 50 ml volumetric flask, add flow meet 45 ml, ultrasonic processing (power 250 w, frequency of 20 KHZ) 30 minutes, remove and cool off, with mobile phase to scale, shake well, filtration, quick.

Measurement precision respectively from the reference substance solution with each 10 mu l solution, injection liquid chromatograph, determination, quick.

This product includes glycyrrhizic acid (C42H62O16) shall not be less than 2.0%.

[up] to remove impurities, washing, nourishes, cut thick slices, dry.

"Sexual flavour" gan, ping.

[to the] for centering, lung, spleen, stomach.

Attending 【 function 】 tonifying spleen yiqi, qingrejiedu, expectorant cough, pain, and the medicine. Used in spleen and stomach weakness, languid, palpitation and shortness of breath, cough phlegm, rou GUI, limb twin acute pain, carbuncle swollen chuangdu, reduce drug toxicity, high.

【 usage and dosage 】 1.5 ~ 9 g.

【 note 】 unfavorable with Beijing spurge, yuanhua, euphorbia kansui.

【 storage 】 ventilated, dry place, moth-proofing.

【 from 】 "Chinese pharmacopoeia"

The classification of licorice

Red-skinned liquorice slice

Wild beige liquorice slice

Wild liquorice slice

According to the classification of origin

The licorice goods generally divided into east licorice and USES two kinds of grass.

East licorice: also known as the east grass. For the native to northeast, hebei, shanxi and other places.

USES grass, also known as the west grass. Is produced in gansu, Inner Mongolia, qinghai, shaanxi, xinjiang and other places.

In addition to the following traditional name of commodity:

Liang grass: from Inner Mongolia YiKeZhaoMeng adapted area.

Report to grass: produced in ningxia BaMeng arap left flag. Used to think and report to the grass outside the beam quality optimal, tunnels for medicinal materials.

West town of grass in Inner Mongolia YiKeZhaoMeng this flag and ningxia TaoDong PingLuo area. Belong to the west grass.

Rivers on the grass in Inner Mongolia flag YiKeZhaoMeng pull dart area. Belong to the west grass.

While the grass; From jingbian-yanshuiguang pipeline and sense area, north of shaanxi. Belong to the west grass.

Northwest grass; Produced in minqin county, qingyang, the beatles, yumen, etc. Belong to the west grass.

Near rivers under the grass in Inner Mongolia baotou tumed flag, togtoh and salinger's resign. Belong to the west grass.

Northeast grass: native to eastern Inner Mongolia, liaoning, zhao wuda union the HuMeng ZheMeng in jilin, heilongjiang, etc. Yu Dongcao.

Xinjiang grass: produced in xinjiang. Flat in west grass.

Licorice processing and classification

The leather licorice: liquorice, with fur, fur with the skin. Reserved for processing after the cork.

Licorice powder: scraped and liquorice, fur, grass, grass powder. For processing after scraping to cork, cut growth period.

Licorice: as growth period, in the process of processing into the person.

Licorice section; Also known as powder, grass, grass. For filling in licorice root and rhizome have parts made of dark brown resin material.

Licorice: also known as a knot in one's leather, a knot in one's head. For the reed header at the top of licorice root.

Licorice root tip: also known as grass shoots, grass shoots. For the peripheral part of liquorice root or fine roots.

To skin fine and tight, mass vertical weight, red brown, dry powder, sweet thick, no impurity is preferred.

Prescription of licorice

Licorice, grass, licorice, cutting the grass, main licorice, grass tip, licorice root tip, sward tip, etc.

Prescription of licorice, sward licorice. For the original medicinal materials to remove impurities, wash and nourishes slice, born in medicine. Be heat-clearing and detoxifying.

Cutting the grass or main licorice, licorice, honey honey liquorice. Living licorice slices and mix with honey, again to not glue the hand out stand out, and then used as a medicine. Partial Yu Run lung and.

Grass shoots, licorice root tip, grass shoots are liquorice root tip or fine root, rinse and cut into small sections as a medicine. Be clear heat diuretic.

Licorice main points of cultivation

licorice

Licorice clinical dosage to heavy, big volume. In today's western development opportunity, licorice effect better, returning farmland to forest, ecological reconstruction project, soil and water conservation function is stronger. Shaanxi farmers and western people reflect, the licorice seeds to the ground can casually emergence, especially strong drought resistance, licorice growth in the northwest, north and northeast and other places.

Licorice, adversity-resistant perennial herbaceous plants. In late autumn, pods split, grain to walk the earth with the wind, natural reproduction. Tall and upright stems; Such as column, 3-4 cm in diameter, big five or six centimeters, one meter long, most elderly people up to three or four meters. Upright, leaves alternate, odd situation frond, lobular 7 ~ 17, the oval, oval raceme altar, lavender, red butterfly flower. Oblong fruit, sometimes a sickle or cyclic bending, densely brown hairy glandular hairs. Oblate seeds. Flowering in July 6 ~, fruiting 7 ~ 9 months.

Licorice more grow in arid and semi-arid desert steppe, desert margins and loess hilly area, the fields in Yellow River irrigation area of the field and the beach is also easy to breed. Its strong adaptability, strong resistance, not the kui is a drought-resistant plant kingdom, dou sand pioneer. Hi sunny, sunshine long, low temperature dry climate. Appropriate chooses soil deep, drainage good sandy loam cultivated. Used for the propagation of seeds or roots, but the roots grow fast. Like dry climate, cold, wild on the dry calcareous, good drainage, sandy loam cultivation of underground water level is low. Avoid high underground water level and waterlogged lowland acidic soil. Neutral or slightly alkaline soil as well.

The national assembly of Chinese herbal medicine: licorice

Licorice medicine name 】 【

M: o "pinyin" G ā n C

"Alias" sweet grass, red licorice, licorice powder, powder of grass

【 origin 】 for leguminous plants of the genus Glycyrrhiza radix glycyrrhizae Glycyrrhiza uralensis he. The roots and rhizomes. Seeds of wild autumn, excavation of cultural product in 3 ~ 4 years later, the excavation of, in the autumn to remove residual stems, according to the thickness respectively to dry.

"The original form" perennial herbs, 30-100 cm tall. Root stout, and cylindrical, sweet taste, the skin red brown or dark brown. Stems erect, base with wood, white hair and hairy glands. Singular pinnate alternate, petiole ca. 6 cm, stipule early fall; Lobular 7 ~ 17 pieces, ovoid elliptic, 2-5.5 cm long, 1 ~ 3 cm wide, apex obtuse, base rounded, glands and hair on both surfaces. Summer axillae drew raceme, dense; Calyx bell-shaped, pierced by short hair and hairy glands; Butterfly corolla reddish purple, 1.4 2.5 cm long and big flag, rectangular shape elliptic, base with short claw, wing flap and keel has long claws, two body stamens. Pods strips oblong, often dense, sometimes a sickle and cyclic bending, 6 ~ 9 mm wide, densely covered with brown spines hairy glands; Seeds 2 ~ 8 grain, oblate or slightly kidney.

Born in dry grassland habitat division 】 【 and sunny slope. Distributed in the northeast, north China and shaanxi, gansu, qinghai, xinjiang, shandong and other regions.

"Culture" like the dry weather. Suitable for growing in sandy soil and sandy loam, but unfavorable in regions with high underground water level of the plant. Seed breeding, dibbling (drilling can be), with around 30 ℃ water before sowing seed sowing after 2 ~ 3 hours. 1 Chinese foot spacing, hole spacing 5 inch open hole, hole 2 inches deep, dibbling each kind of 5 ~ 10, covering five points, seeding rate 3 ~ 5 kg per acre. During the period of growth, in addition to the seedling stage, unfavorable and overmuch water. According to application of nitrogen and phosphate fertilizer.

Roots and rhizomes contain chemical composition 】 【 glycyrrhizin (glycyrrhizin, glycyrrhizic acid namely glycyrrhinic acid, C42H62O16) 6 ~ 14%, and for the composition of liquorice sweetness, is a kind of triterpenoid saponins. Glycyrrhizic acid hydrolysis to produce a molecular glycyrrhetinic acid (glycyrrhetic acid is glycyrrhetinic acid, C30H46O4) and two molecules glucuronic acid (glycuronic acid, C6H10O7). And containing a small amount of licorice yellow glucoside (namely liquiritin liquiritin, C21H22O9, as a kind of flavanols flavanone glucoside, its aglucone liquorice essence liquiritigenin,, bitter glucoside C15H12O4 and licorice glycyamarin), licorice yellow glucoside (iso - liquiritin, C21H24O9), dihydroxy glycyrrhetinic acid (dihydroxyglycyrrhetic acid namely grabric acid, C30H46O5), liquorice landmines (licoricidin C25H32O5, namely, 3 ', 6 - two different pentene - 2 ', 4 ', 5-3 hydroxy different flavane), liquorice alcohol (glycyrol C21H18O6), 5-0 - methyl licorice alcohol (5-0 - methyl glycerol, C22H20O6), licorice alcohol (iso - glycyrol, C21H18O6), in addition, it contains 3.8% mannitol (mannite), glucose, sucrose, malic acid, 2.4 ~ 6.5% betulinic acid (betulicacid C30H48O3), asparagine, tobacco and acid, life element (biotin, C10H16O3N2S) 296 micrograms per gram, trace volatile oil of radix glycyrrhizae characteristic odor source and starch, etc.

[pharmacological action] 1. Detoxification: glycyrrhizin or its calcium salt has the strong detoxification, for diphtheria toxin, tetanus toxin has strong detoxification, for some allergic diseases, animal experimental hepatitis, fugu poison and snake venom has also detoxification. The detoxification mechanism may be various, by way of physical, chemical precipitation, adsorption and combination, strengthen the liver detoxification function and glycyrrhizin hydrolyzate glucuronic acid is the active components of detoxification.

2. The anti-inflammatory and anti allergy: glycyrrhetinic acid on rat cotton ball granuloma edema, formaldehyde, tuberculin reaction, subcutaneous granulation cystic inflammation has inhibitory effect. Glycyrrhizic acid ammonium, sodium glycyrrhetinic acid can effectively affect the subcutaneous granulation hyperplasia of cystic inflammation effusion and period, the role of intensity weaker than or similar to cortisone. Glycyrrhizic acid the anti-inflammatory effects of various agents, by the activity of succinic acid salt is higher, but also big toxicity. Licorice anti-inflammatory allergy, the principle of resistance has not been fully elucidated.

3. Licorice has expectorant effect, can promote the throat and bronchial secretion, make it easy to phlegm cough up.

4. Glycyrrhetinic acid derivant of guinea pig and the cat experimental cough had obvious antitussive effect.

5. Licorice various preparations on rat experimental gastric ulcer has obvious inhibitory effect. Licorice extract water protection of gastric mucosa, the effect of treatment of gastric ulcer. According to clinical observe with pharmacological research, licorice water extract can increase gastric mucosal cells "has sugar amine" ingredients, make gastric mucosa from injury.

6. The impact on the secretion of gastric juice: licorice liquid extract after lavage, can adsorption hydrochloric acid in gastric juice, so can reduce gastric acid concentration, but after absorption can also play a role. Also has inhibitory effect on basis of production.

7. Spasmolysis: liquorice decoction, liquid extract in vitro intestinal canal all have inhibition to animals, to acetylcholine and barium chloride, histamine causes of intestinal cramps have spasmolysis effect. Licorice root in vitro intestinal canal and in the body of the stomach to animals have a relaxation.

8. Licorice on animal experimental liver injury, the degeneration and necrosis significantly reduce liver, liver intracellular accumulation of glycogen yuan and RNA content most or close to normal, a significant reduction in the serum Alt activity, suggests that licorice - with the role of liver injury.

9. Adrenal cortical hormone kind function: licorice can make many kinds of animal urine sodium and discharge reduction, increased potassium eduction, serum sodium, blood calcium, adrenal cortex ball with atrophy. Licorice can make urine 17 - hydroxyl corticosteroids discharge increases free type, combination type, small dose of thymic atrophy, adrenal weight increase, the beam shape layer range widening, low vitamin C content of adrenal gland. Licorice can significantly enhance and extend the examination of pine. Licorice adrenal cortical hormone kind function principle, some people think that the chemical structure of the glycyrrhetinic acid similar to adrenal cortical hormone, is similar, is a kind of direct action; Also some people think that is a kind of indirect role that glycyrrhetinic acid inhibits adrenal cortical sterols in the body of damage, and thus blood corticosteroid levels increase, the obvious, which appear in the adrenal cortical hormone kind function.

10. Licorice has the effect of against acetylcholine, and can enhance the cardiac function of adrenaline.

11. Cancer: glycyrrhetinic acid on rat experimental myeloma and ascites liver tumor inhibition. The airy ascites carcinoma has inhibitory effect on mice.

12. Licorice with yuanhua share has the opposite effect: the total leaching toxicity than points leaching group increased significantly, yuanhua Shared with liquorice, diuresis, xie next role is restrained, can enhance toxicity of licorice.

[up] main licorice: ripe honey liquorice slice to join smelting with a little water, mix well after a bit stuffy, put in the pot and stir-fry until deep yellow and not glue the hand, take out the cool (per 100 jins with ripe honey smelting 25 ~ 30 kg).

"Sexual flavour" gan, ping.

Attending function 】 【 qingrejiedu, runfei cough, to reconcile the medicine; The main licorice can tonifying spleen yiqi. Attending sore throat, cough, spleen and stomach weakness, gastric and duodenal ulcer, hepatitis, hysteria, carbuncle furuncle swollen poison, drug and food poisoning.

【 usage and dosage 】 0.5 ~ 3 money.

【 note 】 is unfavorable and euphorbia kansui, spurge, yuanhua, seaweed.

1. The compound 】 【 gastric and duodenal ulcers: liquorice 10 grams, 15 grams, egg shell stramonium 0.5 grams, altogether grind fine powder, each take 3 g, 3 times a day.

2. Hysteria: (wheat jujube soup) licorice 5 money, big jujube 1, 4 money floating wheat, water decoction.

3. Guilty nervous gas, clavus generation beats (early) : main licorice, codonopsis, radix rehmanniae, donkey-hide gelatin, dwarf lilyturf, cannabis each 3 money, cassia twig 1.5 money, 3 slices ginger, jujube 5 pieces. Yin deficiency with internal, night sleep soundly uneasy to cassia twig, and ginger, add spirit magnet 5 money, oyster 1; Qi deficiency and astragalus three money, fructus schisandrae 1.5 money.

【 note 】 1. Commodities licorice main points of two kinds of licorice and USES grass, east east northeast licorice agriculture is in the northeast and Inner Mongolia, the original plant main licorice department of Glycyrrhiza uralensis. He, USES grass advocate in the northwest of Inner Mongolia western eastern, southern gansu, qinghai, northern shanxi and shaanxi, the original plant also is such.

2. USES grass native to xinjiang and gansu province in northwest, in addition to the licorice, include:

(1) light fruit licorice Glycyrrhiza glabra l., distributed in xinjiang. Similar to licorice root element.

(2) the swelling fruit licorice Glycyrrhiza inflata Batal., liquorice root in local and light liquorice were licorice medicine. Distributed in xinjiang and northwestern gansu province.

(3) the yellow licorice Glycyrrhiza kanscensis Chang et Pang, MSS., distributed in gansu and xinjiang. Texture is licorice burning time.

The "national assembly of Chinese herbal medicine" [from]

The Chinese medicine dictionary: licorice

Licorice medicine name 】 【

M: o "pinyin" G ā n C

"Alias" beautiful grass, honey, "the classics"), sweet grass, grass Lu (" don't record "), the old (tao hongjing...), informed (for beads), grass powder (qunfang spectrum), sweet grass (Chinese medicine plant), sweet root (" TCM "), the great grass (heilongjiang Chinese medicine).

【 origin 】 "materia medica"

【 origin 】 for leguminous plant licorice roots and rhizomes. Excavation of autumn, remove stem base, branches, fibrous root, etc., cut into the appropriate length of period, sun to dry, into small bundles, the sun to dry. Cut, who also have outside the cork, referred to as the "powder grass". Dry ventilated place, mouldproof decay.

"The original form" perennial herbs, about 30-70 cm tall, rarely up to 1 m, rhizome cylindrical; Taproot is very long, bulky, skin reddish brown to dark brown. Stems erect, slightly woody, white hair and gland scale or glandular hairs. Odd pinnate, stipule lanceolate, early fall; Lobular 4 ~ 8 pairs, petiolule very short, 1 mm long xu; Small leaf ovoid, elliptic or accidentally nearly circular, oval 2-5.5 cm long, 1.5 ~ 3 cm wide, apex acute or nearly obtuse, base usually rounded, glandular scales on both surfaces and short hair. Raceme altar, dense, 5 ~ 12 cm long; Calyx bell, about 1/2 of corolla and slightly long, calyx teeth 5, lanceolate, calyx tube slightly longer, short hairy and glandular scales; Corolla violet violet, about 14 ~ au mm long, flag is large, oblong elliptic, apex rounded or emarginated, lower have short claw, keel, straight is the shorter of the wing flap, all have long claws; Stamens 10, 2, filaments length is differ, anther size; Pistil 1, ovary sessile. Including linear oblong, bending sickle or assumes the circular, Chang Kuan 6 ~ 8 mm, densely covered with brown spiny glandular hairs. Seeds 2 ~ 8, oblate or kidney-shaped, black smooth. Flowering June to July. Fruiting 7 ~ 9 months.

Was born in xiangyang dry calcareous grassland habitat division 】 【 sandy soil, the Banks of the river, etc. Distribution in northeast, northwest, north China, etc. Agriculture in Inner Mongolia, gansu; Followed by shaanxi, shanxi, liaoning, jilin, heilongjiang, hebei, qinghai, xinjiang and other places. In Inner Mongolia YiKeZhaoMeng adapted by product quality, and the optimal.

【 description 】 dry root is long cylindrical, not branched, cut growth 30 ~ 120 cm long, 0.6 3.3 cm in diameter. Licorice with skin, skin elastic, red brown, brown or gray brown, with significant wrinkles, grooving and sparse of fine roots, lenticels, small bumps, show dark yellow. On both ends of the section level, cut the central slightly under. Solid and heavy mass. Section fibrous, yellowish-white, powder, there is a clear ring and chrysanthemum heart, often forming fissure. Micro with special aroma, sweet taste and special. Rhizomes shape similar to the root, but the surface has bud mark, a transverse central myelinated. Powder grass looks flat, light yellow, fibrous, a longitudinal crack. Have thin skin tight, licorice with the skin wrinkles ditch, red brown, qualitative solid, powder, section yellowish-white is preferred; Skin coarse, gray brown, mass pine, powder, small cross section of the deep yellow; Skin is dark brown, qualitative hard, section tan, taste bitter is not used as a medicine. The better than with skin licorice powder grass.

Licorice root and rhizome containing chemical composition 】 【 glycyrrhizin, for glycyrrhizic acid, glycyrrhizic acid) of potassium, calcium salt. Still contain liquiritin liquiritin, liquiritin yuan (liquiritigenin), liquiritin (isoliquiritin), licorice yuan (isoliquritigenin), new liquiritin (neo - liquiritin), novelty liquiritin (neoiso - liquiritin), etc.

[pharmacological action] glycyrrhetinic acid has inhibitory effect to rat transplanted OberlingGuerin myeloma, glycyrrhizic acid, sodium glycyrrhetinic acid ammonium and mixtures of glycyrrhetinic acid derivant of airy mice ascites carcinoma and sarcoma has inhibitory effect, even if the oral is also effective. Glycyrrhizin glucoside, licorice water on rat's abdomen and airy ascites cancer cells in mice liver cancer can produce a change of morphology, glycyrrhizin could inhibit subcutaneous transplantation yoshida sarcoma.

[up] licorice: jian to impurities, wash and water soaking and eighty percent through, remove, nourishes slice, dry. Honey liquorice: liquorice slice, add cooked with boiling water with a little honey, and mix well, a little stuffy, set the pot and stir-fry until the mixture gently into deep yellow, not glue the hand for degrees, remove to cool. (every 100 jins, licorice pieces from the refined honey 25 ~ 30 kg)

(1) the tripterygium wilfordii cannon main theory ":" whoever makes licorice, must go to the end point, soaked in wine, steamed, from the third to the sixth, suddenly and violently dry, smooth file. A seven two jins with crisp, coated with acupuncture, crisp do. And gun to red and yellow inside and outside with a good first."

(2) "of materia medica", "the sense of main licorice is dip in with running water wet main, until cooked to bare skin. Or use the hot water."

(3) the need to match material medica: "japonica rice and stir, or honey."

"Sexual flavour" gan, ping.

(1) "this sutra:" gan, ping."

(2) "don't record" : "drug-free."

(3) "Ben yan yi", "cool."

(4) "the pearl capsule", "gan, ping; main, wen."

"To the" into the spleen, stomach, lung.

Material medica: (1) the soup "into the fa jue, lunar, shaoyin meridian."

(2) the tripterygium wilfordii processing medicinal solution ":" into the heart, spleen by."

(3) "Ben tong xuan" : "into the spleen and stomach."

(4) "huang solution" : "of lunar, foot lunar spleen lungs."

And the function of attending 】 【 priorities, runfei, detoxification, reconcile the medicine. Main use, spleen and stomach weak, eat less, abdominal pain, loose stools, weary fever, impotent lung cough, palpitations, chronic ulcerated; Born with, sore throats, peptic ulcer, ulcer ulcers, antidote to the poison and food poisoning.

(1) "the classics", "five six mansion was not evil, strong bones and muscles, long muscles, bally, Jin Chuang swollen, detoxification."

(2) "don't record", "middle temperature gas, vexed with shortness of breath, dirty cough, thirst, meridians, the flesh, the drug detoxification."

(3) "medicinal theory", "Lord, stomach pain, cure chronic ulcerated, except for the abdominal distension full; tonic five zang-organs, making the toxicity; kidney internal injuries, a Yin is (not) impotent; housewife blood drain lumbago; virtual and how hot; increases."

(4) the solar corona material medica son: "requiem 'o. Fill WuLaoQiShang, everything is deficient, insomnia, forgetfulness, boredom. Nine qiao, lotaustralin, yi aquiculture, strong bones and muscles, hot and cold."

(5) "pearl capsule" : "blood, nourishing the stomach."

6 compendium of material medica: soup "to treat lung impotent purulent blood, and puke; the sore carbuncle of five hair, work with astragalus."

7 "of materia medica", "XieXiaoEr congenital disease, surprised Gu, decrease internal heat pain."

Today "Chinese medicine plant map" : "treat peptic ulcer and jaundice.

【 usage and dosage 】 oral: decoct soup, 0.5 ~ 3 money; Or the pill, powder. External use: at the end of the research contents or Fried washed.

【 note 】 do not taken empirical filled with abdominal distension.

(1) the huang glosses) : ", dry paint, bitter arguments to make. Evil polygala. Reverse spurge, yuanhua, euphorbia kansui, seaweed siwu."

(2) "medical introduction" : "at the beginning of diarrhea, is not available."

【 compound 】 (1) RongWei deficiency, viscera of weakness, and heart abdominal distension full, all don't think food, bowel diarrhea, ou Hui inverse vomit: ginseng (reed), poria cocos (peeled), liquorice (main), extracted by the uniform. Take two money, is the end of the fine, each a lamp, water frying to seven points, oral, or when. In some salt, consomme point also. (the pharmacopoeia sijunzi decoction)

(2) to treat lung expression paralysis spit saliva foam without cough: licorice four two (main), dried ginger (gun). Prescription fine cut to three litres of water, cook for a litre of five together, go to chamber, temperature to suit. (synopsis of licorice root dry ginger soup)

2 two (3) to treat heat syndromes: licorice, pig bile leaching five nights, Lu main fragrant, dao luo for the late, and refining honey pill, such as green beans, eat mint soup after 15 pills. (the holy dhi total recorded "cool diaphragmatic pill)

(4) typhoid cure clavus generation, cardiac nervous: licorice (main) four two, ginger (cut) three two, two two ginseng, radix rehmanniae 1 catty, cassia twig (peeled) three two, two two donkey-hide gelatin, ophiopogon (heart) half a catty, cannabis half a liter, jujube (brake) 30 pieces. Right nine flavour, with wine and seven liters, eight liters of water, cook first eight, three litres, go to the chamber, the glue Yang away, take a liter, day three suits. (treatise on febrile disease main licorice soup, a complex pulse soup)

(5) treat shaoyin disease 2, 3, sore throat, and licorice soup does not claim: platycodon grandiflorum one or two. Licorice two two. In two flavours, with three litres of water, boil a liter, slag, temperature points again. (treatise on febrile disease, platycodon grandiflorum soup)

6 cure insomnia, irritated heat, palpitations, licorice a money, including five points to one of money. The water decoction. A daily dose, divide second drink. (jiangxi ganzhou grass simple medical herbs prescriptions assembly)

Two copies of all landowners treat malaria: licorice and euphorbia kansui a. Total at the end of the porphyrization, in two hours before the onset of taking a belly button, put to tape or small plaster stick. Yindong (xuzhou unilaterally prescription new doctor therapy)

Today to treat gastric and duodenal ulcers: seller corrugated child two (calcined research) at the end of the five, one or two (r) at the end of the licorice. Blending, take 2 each money, 3 times a day. New doctor (liaoning (Chinese herbs data yindong GanLeng scattered) denominated in licorice powder 1.0 grams, egg shell powder 1.5 g, stramonium powder 0.05 g. Blending, before meals or pain, take 3 grams each, three times a day. (liaoning, materials of Chinese herbal medicine new doctor therapy yindong gump shell powder)

Pet-name ruby woman dirty mania, like sadness, want to cry, a few snaps: licorice, three two wheat a liter, jujube has ten. On the three to six litres of water, three litres, wen three suits. Also temper. (synopsis of gansu wheat jujube soup)

Attending to treat smallpox polydipsia: bisected powder, liquorice root (main), trichosanthes kirilowii. Water decoction. (" RenZhai attaches to party ")

⑾ baby eye astringent, month eyes does not open, closed or swollen, photophobia, and even bleeding, chronic: licorice, with pig bile, as at the end of each Gan to reconcile with a little rice irrigation. (the new baby book)

⑿ for fire burning boil soup: liquorice decoction with honey. (" monster card and parties ")

[13] hong Yin wet itch: licorice a foot, and cut, with five litres of water, boil three litres, washed, the day 3, 5 degrees. (" the keeping in good health with party ")

[14] for pesticide (1059, 1605, 4049, organophosphorus preparations) poisoning: licorice four two, five money talcum powder. When the liquorice decoction soup, cold after blunt talcum powder, take. Even the medicine three times a day. Yindong (xuzhou unilaterally prescription new doctor therapy)

⒂ signaled poisoning, the arsenic poison: licorice with black beans cooked sauce, taste drink. (" compendium MengQuan)

Three money has displayed for lead poisoning: licorice, almond four money (peeled, tip). Two flavour decoction, twice a day, can take three to five days. (" health "in October 1956)

⒄ typhoid fever sore throat (shaoyin disease). 2 two with liquorice, honey water moxibustion, 2 liters of water, boil a liter and a half. Take five, each taken twice a day. The name "licorice soup".

⒅ lung heat sore throat (hot). Use two Fried licorice 2, platycodon grandiflorum (the water that clean out rice overnight) one or two, add gelatin half jins. Take five money, each water decoction.

Trick lung impotent (head dizzy, spit saliva foam, frequency of urine, but don't cough). Use moxibustion four, two two cannons dried ginger, licorice three litres of water, boil half, a few times. The name "licorice dry ginger soup".

⒇ impotent long lung syndromes (evil cold have a fever, joints, rinse salivary than). With three two moxibustion licorice, porphyrization. Take a daily money, webbed hands trine tuning.

Pediatric heat syndromes (21). 2 two with liquorice, in pig bile at five days, remove the porphyrization after moxibustion, and honey into balls, such as green beans. Take ten each pill, after dinner, send the mint soup. The name "cool every pill".

(22) infants born was closed. With liquorice, orange one money, half bowl of water decoction.

Pediatric pinch of tune (23). With licorice out two and a half, decoction, spit saliva. To milk a little mouth.

Babies (24) and chronic (acerbity, photophobia, swollen shut, and even bleeding), with a refers to the long, licorice pig bile moxibustion, fine grind. With rice juice with a little gulp.

(25) children enuresis. With big licorice first decoct soup, take it every night before bed.

(26) children with blood in his urine. With licorice 122 money, add water liuhe, Fried into composite. One year old son taken as a day.

(27) children lean. Three two with liquorice, jiu jiao, thin, and honey into pellets, such as green beans. Take five pellets, each under the warm water. Taken twice a day.

(28) pullorosis artificially infected in red. Licorice a foot long, after moxibustion split, with weak water a liter and a half, Fried to take.

(29) tongue swollen mouth (not to treat life-threatening). With liquorice and cooked soup, hot rinse, spit saliva juice at any time.

Aphtha (30). With liquorice 2 inches, alum a (such as millet), put the mouth with fine chew and swallow.

(31) back gangrene. Three two with liquorice, dolly, increase the wheat flour. Two, a total of research. Some good drip into the vinegar and water, make a cake, hot compress gangrene. Change again cold. Not into within the pus can, early break is pus. To add astragalus virtual body porridge. Party again: licorice one or two, moxibustion, dolly, into a litre, overnight, stirring water bubbles, the bubble off, only drink licorice water.

Various ulcer (32). Three two with liquorice, moxibustion, cheddar, half immersed in the wine; Take black lead another piece, melt juice for the wine, not long, nine times repeatedly. The patient drink this wine to drunk, ulcer convalesce. Party again: licorice 2 jins, lamented, water soak overnight, knead in concentrated juice, slow boil into a paste, organize jar. One, two spoonfuls each. The name "the old cream". Swelling to poison, efficacy significantly.

(33) early breast carbuncle. Use moxibustion licorice two money, new pumping decoction. Suck the nipple, avoid to jam.

Smallpox (34). With moxibustion liquorice, trichosanthes kirilowii, Fried water service.

(35) vaginal vertical carbuncle (born before and after the anus, incipient such as pine nuts, such as lotus seeds, red like peaches. Pus break, and hard to cure). With liquorice one or two, streams of water have a bowl, small fire slowly dipped in water of moxibustion. From early to lunch, to the water. Split view, licorice center for water embellish. Remove fine file, add the two bowls of Fried into a bowl of wine. Warm clothing. After two doses, heat disease better, but must be approved by 20 days, swelling pain will disappear.

(36) temperature vaginal itching. With liquorice decoction soup, three, five times a day.

Frostbite roak (37). With liquorice decoction washed first, and then with rhizoma coptidis, radix scutellariae, at the end of the research for silver powder, sesame oil with water apply.

Sharing (38) soup. Put on the skin with honey liquorice decoction.

"Drug, meaning" : each paper 】 【 "licorice, born with cool and purging fire, the hash table, carbuncle swollen, sore throat, and the drug detoxification, in addition to the stomach heat, to urine tube of pain, this cool in addition to the force of heat also. Main with warm and fill in the main slide xie pixu (spleen deficient), stomach empty thirst, fever cough, shortness of breath, servitude is deficient, the work of the GanWen help spleen also. But thick taste too sweet, unfavorable use tonic, fear of love diaphragmatic don't think the food is."

The clinical application of 】 (1) treatment of gastric and duodenal ulcer

Have a good recent curative effect. According to more than 50 cases to 200 cases of observation, the efficient around 90%, especially in the activity have pain symptoms curative effect is better. General medicine in 1 ~ 3 weeks, the pain disappeared or significantly reduce, defecate occult blood turns shade; More than half of X-ray showed niche disappear. Licorice for the curative effect of gastric ulcer is better than that of duodenal ulcer, for fresh ulcer of the older a better, symptoms improved after treatment earlier than X-ray changes; But for the canker of complications, are often invalid; The long-term curative effect is satisfied, half of all cases recurrence phenomenon. Usage: seller licorice liquid extract: 10 ml each time, three times a day, 4 ~ 6 weeks for a period of treatment; Also have daily amount to only 15 ml. But some people think that, every time with 1 ml, 4 times a day, is a more suitable dose. Denominated in 33% of licorice extract solution: daily 15 ~ 30 ml, three points, 4 weeks as a course of treatment. An licorice powder: 2.5 ~ 5.0 g each time, three times a month, amuse (3 ~ 4 weeks. Registering in liquorice pill: 12 ~ 15 grams per day, three points, amuse six weeks. Experience has shown that the curative effect of licorice powder is better than that of liquid extract, licorice root whole licorice effective components of licorice powder contains; And licorice liquid extract contains alcohol and chloroform, canker is not fitting for, using licorice extract solution without the disadvantages. Side effects: glycyrrhiza preparations can happen deoxycorticosterone sample function, electrolyte balance, make the blood sodium retention, potassium decreased, causing increased blood pressure and edema, some cases hypokalemia in ecg changes, individual cases diabetes. For high blood pressure and edema, general limit salt intake can disappear after the drug was stopped, does not affect the treatment. Treatment is limited to 4 ~ 6 weeks, exceed this limit, the cardiac involvement opportunities is increasing. In order to prevent edema, blood pressure and other side effects, someone once amalgamative use double hydrogen grams of urine. Clinically observed, such as the sorbent with small dose of licorice extract and astringent, or with liquorice extract treatment, side effects greatly reduce or avoid completely, but curative effect also decreases. Given the side effects of licorice and drainage storage sodium potassium, reason should be banned for kidney disease, high blood pressure patients. Long-term application of myocardial damage caused by also should be attention. In addition, the clinical has given priority to with liquorice in combination with other drugs, such as cuttlefish bone, corrugated, dried tangerine or orange peel, honey, such as treating canker, the effect is better.

(2) treatment of Addison's disease

According to a handful of cases observation, curative effect is significant, for patients with mild or early can make the patients gain weight, physical enhancement, improve appetite, increased blood pressure, skin pigmentation, serum electrolyte concentration improved, increased concentration of serum sodium and chloride and potassium decreased to the normal range, 17 - ketone sterol excretion in urine increased; Some cases of X-ray showing enlarged heart clear, can reach the normal range. For patients with severe or late, separate application effect is not very ideal, even can't prevent the happening of the crisis, but must be combined with corticosterone to work; With both, can decrease the latter's requirement, as a complementary role. Licorice treatment according to the theory of the disease, is thought to be the action of the active ingredients of licorice glycyrrhetinic acid and deoxycorticosterone have similarities, can make the sodium, chloride, and water retention in the body and potassium ion concentration is reduced, thus received effective treatment. Also has the effect that think licorice in the treatment of the disease, and aldosterone is most similar in nature. Side effects: excessive can occur when the edema, asthma, headaches, accompanied by hypertension, pulmonary edema, for older patients can cause cardiac asthma, etc. Usage: use liquid extract, licorice root but dose size must be depending on individual circumstances. Around the report quite inconsistent, the daily amount of useful 15 ml, useful 20 ~ 30 ml, has gradually increased to 30 ~ 60 ml. Also useful licorice extract 20 ~ 45 grams per day, or 6 grams of glycyrrhizic acid, glycyrrhetinic acid or 3 ~ 5 g. Continuous use maintenance dose also vary from person to person, a few weeks later, the patient can be increased sensitivity of licorice, the dose should be gradually reduced, in some cases only began to amount to maintain the 1/1 o. There are people with licorice powder, 15 ~ 30 grams per day, think its curative effect is better than that of licorice extract.

(3) treatment sheehan's syndrome

Licorice powder 10 grams, 3 times a day, at the same time cooperate with methyl testosterone, thyroxine, glucose, vitamins, etc. Try to treat type 1 case of hypogonadism sheehan's syndrome, drug use body temperature to normal after 1 week, spiritual improvement; Two weeks after weight gain, eating as usual; After 1 month of grip strength increased by 10 pounds to 18 pounds, can provide for oneself life, blood pressure to normal range, apex area noise disappear, fasting blood glucose of 88 mg % % to 110 mg, sexual performance; Menstrual bleeding in 3 months. The following - girl, mother and daughter are healthy.

(4) in the treatment of diabetes insipidus

5 grams for the licorice powder, 4 times a day, try to treat two cases of disease collectors has 4 ~ 9 years of diabetes insipidus, received a certain effect. Patients on admission of water intake at 8000 ml, urine significantly reduced after taking this medicine, maintained at 3000 ~ 4000 ml, 1 case of the minimum quantity of urine was less than 2000 ml

5. Treatment of tuberculosis

At the same time in the application of the chemotherapy medicine and glycyrrhiza preparations, the long-term chemotherapy medication the effect not beautiful or progression of the disease patients, to receive better curative effect. Not only for infiltration STD focal and pleurisy can make inflammation absorption, poisoning symptoms and solutions, short-term disappear, but also for the spherical lesions, pyothorax also has a good effect, can shorten the treatment time. According to observation, 10 cases to dozens of cases after symptoms improved significantly or disappeared in most of the cases, blood sedimentation, sputum bacterium turns shade; X-ray showed progress, lung infiltrates lesions absorption or disappear, pleural effusion in gradually reduce and even disappeared, fiber type hollow hole. Think licorice have similar deoxycorticosterone role, as the source of its occurrence curative effect; Side effects are also similar to deoxycorticosterone, such as increased blood pressure, edema, individual move slowly or tachycardia, extrasystole. Therefore, high blood pressure and heart organic disease or cardiac insufficiency should be careful. Usage: seller decoction: general daily use 50 grams of crude drug, decoct juice three times; But also have daily quantity as low as 18.6 grams. Denominated in liquid extract: 5 ~ 10 ml per day, or 10 ~ 15 ml, add water to 60 ml. Three times.

6. Treatment of bronchial asthma

5 g with licorice powder or licorice liquid extract 10 ml, 3 times a day. Try 3 cases of chronic intractable chronic bronchial asthma, achieved significant effect. Asthma symptoms disappeared or improved in 1 ~ 3 days, bronchial flute in 11 days disappear entirely, vital capacity increased significantly. Among them 1 case of recurrence, and then treated with liquorice is still valid, when the other useful licorice liquid extract treatment of 4 cases, also the effect.

All landowners treat infectious hepatitis

100% of liquorice decoction 15 ~ 20 ml, pediatric in half, three times a day. Treatment of 13 cases, jaundice index at an average of 12.9 days back to normal, three in 9.9 days to test the negative urine, liver enlargement in 9.2 days significantly narrowed, liver pain disappeared in 7.8 days

Today the treatment of acute schistosomiasis

According to the licorice have similar deoxycorticosterone pharmacological effects, use it instead of take an examination of pine and promote cortisol treatment of acute schistosomiasis to obtain good effect. General medicine began antifebrile, 1 ~ 2 days after 5 ~ 10 days most of the return to normal, at the same time also by general marked improvement or recovery. Usage: licorice powder 30 grams a day, three times, the heat back up to half the amount to take a week or so. The total course of about 15 ~ 20 days. Auxiliary treatment process appropriate, in combination with other drugs and support therapy.

Pet-name ruby treatment of malaria

With liquorice, euphorbia kansui amount grind powder stick together, from malaria take 30 minutes before the onset of powder, a little on your belly button attached with black patches. The 109 cases. Except 2 cases with drug is invalid not in time, the effect.

Attending treatment of thrombocytopenic purpura

Licorice 1, water decocting 2 times, on, in the afternoon. The 3 cases, all have the effect.

⑾ treat gastrocnemius spasm

Licorice liquid extract adults 10 ~ 15 ml, 2 times a day. The 254 cases, cure has significant curative effect of 241 cases, accounting for 94.8%. Period of treatment the shortest 3 days, the longest 6 days.

⑿ to treat congenital muscular rigidity

Licorice powder, 3 g, 3 times a day into a low salt diet and treatment for 15 days. Try one case of history in the past two years, four days after symptoms have improved, at the end of the course of basic symptoms disappear.

[13] to treat thrombophlebitis

Licorice liquid extract 12 ~ 20 ml per day, or 50 g liquorice decoction, divide three times before a meal. Via treated 8 cases, except for 2 cases improved significantly after hospital discharge, the rest were recovered, local pain, swelling and the strings are disappearing. Think licorice treatment of this disease has anti-inflammatory, analgesic, increase the body resistance and stop the role of granulation tissue hyperplasia. Treatment of individual case of mild edema, and increase blood pressure in the process, deweighting disapper. In addition, with liquorice serving 15 ml liquid extract, (three times), cure 1 cases of thromboangiitis obliterans. Drug use self-conscious symptom disappeared after 3 weeks, the skin turn red, the skin temperature, toes back to normal joint movement.

[14] treatment of cervical erosion

In 1:40 00 potassium manganate fluid first rinse the vagina, dry to dry cotton swabs after licorice liquid extract besmear is on the cervix. Moderate cervical erosion effect is better, and provided for in this law treatment commonly 2 ~ 3 period of treatment (treatment 5 times) can be recovered. Such as trichomonas must cure trichomoniasis, to treat cervical erosion.

⒂ treat inflammation of the skin

With 2% local shi fu, licorice water 2 hours, 15 ~ 20 minutes every time; 12 cases to treat contact dermatitis, generally 1 ~ 4 days or see red subsidise, drainage stops, erosion surface healing, following with zinc oxide cataplasm or topical days namely the calamine lotion. 1 two with liquorice, decoct, wash affected area once a day, has effect on allergic dermatitis as well. Glycyrrhetinic acid also has therapeutic effect for eczema and psoriasis.

Treatment has displayed a cracked in the hands and feet

Take 1 two slices, licorice in 100 ml of 75% ethanol and the strain the immersion, 24 hours with the same amount of glycerol and water mixture besmear put on the skin diseases. Follow-up of 17 cases of severe patients, results are satisfactory.

⒄ treatment eye inflammation

To 5% or 8 ~ 12% glycyrrhizic acid sodium salt solution, or mixed suspension glycyrrhetinic acid (containing 10 mg per milliliter), or 10 ~ 30% of licorice extract liquid drop eye, according to the illness needs, 1 eye drops every 1 ~ 2 hour or drop 3 ~ 4 times a day, for the following eye disease effectively: seller herpes sex ophthalmitis: 60 cases of herpes keratitis, corneal conjunctivitis and bunchy keratitis patients, after 2 ~ 7 days or so, to complete recovery in 56 cases (2 cases of recurrence due to premature discontinuation); Article reports for herpes conjunctivitis regimen 2 ~ 14 days, pain, hyperemia and herpes is gradually reduce and disappear. In lien scleritis, scleritis: observation 4 cases and 5 cases respectively, nodules disappeared within 3 ~ 17 days after medication, 6 ~ 34 on inflammation disappeared. To spring catarrhal conjunctivitis: treatment of 6 cases, itch and conjunctival injection drug use 2 ~ 3, significantly reduce, but recurred immediately after the drug was stopped, and drug control. In addition, for TB irritability keratitis and scleritis, also have the obvious curative effect; For deep keratitis, corneal essence inflammation, corneal stromal inflammation, can alleviate congestion and pain symptoms, but corneal infiltrates change is not obvious; For acute iris ciliary body inflammation can relieve congestion and pain stimulus symptoms, but the former exudate is there a control function in the room, observing the results don't agree with each other. Another had glycyrrhizic acid sodium salt and a small amount of loose and, at the same time take different subcallosal, treatment 1 cases of tuberculous iridocyclitis received good results.

⒅ treat frostbite

Take money licorice, yuanhua every 3, 2000 ml water bath to wash area after frying, 3 times per day (every agent can take 3 ~ 5 times), have burst and necrotic wounds after washing with coptis article gauze bandage. Treatment of hand, foot frostbite, a total of 76 cases after drug use 1 ~ 8 agent, 58 cases recovered, the result is unknown. Practice has proved that the pure red is best, more than half of medical agent 1 bath wash 3 ~ 5 times more namely; For swelling and necrosis of skin wound, swelling disappeared after washing, then falls off necrotic tissue, wounds present fresh granulation tissue, with rhizoma coptidis treatment after the wound is healing quickly; On curative effect after frost crack less, but after a few times after bath wash affected part to make by dry hard into a smooth soft and gradually recovered. For three degrees of frostbite colloid bad dead, can make the pain disappeared after washing, necrotic tissue separation, in the interest of early surgical treatment.

In addition, who is given priority to with glycyrrhiza preparations, in combination with other drugs or therapy to treat severe pneumonia, tonsillitis, concurrent urticaria, small wind nie sex arthritis, hypotension,'s poisoning, brachial plexus neuritis, facial nerve paralysis and a toadstool, cassava poisoning, etc., while the cases is less, but has achieved good effect.

【 note 】 besides the main varieties, there are the following to the genus medicine use.

1) light fruit licorice, also known as: the licorice. Characterized by rime and hydrophobic pilose on local, not glandular hairs, lobules oblong or elongated ovoid. Pods oblong, flat, straight or slightly curved. Distribution of xinjiang.

(2) yellow licorice, its characteristics of upper stem slightly hairy or nearly glabrous. Pods slightly bending sickle, expansion, with glandular hairs. Distribution in gansu province.

(3) swelling fruit licorice, the characteristics of 3 ~ 5, rare seven pieces, midrib glabrous below. Pods oblong, straight, inflation. Distribution of xinjiang, gansu and other places.

[from] the Chinese medicine dictionary