Traditional Chinese medicine brings good news to patients with slow disease

The 2018-09-05 health

China's and the world's population is constantly aging, and the incidence of degenerative, senile and inherited chronic diseases is on the rise, bringing great pressure on medical and health resources and social economy. Therefore, exploring the common pathogenesis of various chronic diseases and controlling the occurrence and development of chronic diseases have become major medical problems that urgently need to be solved, as well as a key element to realize the "healthy China strategy".

Wang yongjun, director of the institute of spinal diseases of Shanghai university of Chinese medicine and professor wang yongjun from longhua hospital of Shanghai university of Chinese medicine, has long been committed to the research of TCM prevention and treatment of chronic diseases. This study proves that "renal sperm deficiency" accelerates the development of chronic diseases and is closely related to the changes in the neuro-endocrine-immune-circulation (NEIC) system, the microenvironment and the biological functions of stem cells, mainly manifested as the low expression of cytokines such as ifn-fu, TSH and TGF tree. The concept of "kidney essence deficiency chronic disease" was innovatively proposed, and the common rules of chronic diseases such as osteoporosis, senile dementia and cervical spondylotic myelopathy were proved to be "continuous stimulation of chronic inflammation, accelerated degeneration and aging, resulting in decreased proliferation and differentiation of stem cells, and reduced ability of tissue repair and compensation".

Use the team also kidney fill fine party to treat 3544 cases of kidney essence deficiency in patients with chronic diseases, significantly improved the clinical manifestations of "kidney essence deficiency", the total effective rate was 85.6%, and improve the level of this kind of disease prevention and control of, fully embodies the "card, and then cure" clinical therapeutics of traditional Chinese medicine science and law, and established from the "kidney" clinical standardized solution treatment on chronic diseases. At present, the research results have been applied in nearly 3,000 hospitals and community health service centers.

The researchers said

Let more research results feed the clinical

Traditional Chinese medicine has the advantage of preventing and curing chronic diseases of bones and muscles

Chronic degenerative aging bones and muscles disease is due to the human body, and because of trauma, factors such as strain, feelings, metabolic disorders, accelerate the degeneration, aging, resulting in areas such as the whole spine, bone and joint, skeletal muscle pathological changes, and the physique "disorder of dynamic and static force balance", partial or whole body pain, swelling, numbness, muscle atrophy, such as the limited activities signs and symptoms of syndrome, including cervical spondylosis, periarthritis of shoulder, lumbar spinal stenosis, lumbar intervertebral disc protrusion disease, osteoporosis and osteoarthrosis.

Based on the experience of the older generation of experts in the discipline of bone injury in longhua hospital affiliated to Shanghai university of Chinese medicine, professor wang yongjun founded the internal treatment "harmonizing method" (internal regulation of qi and blood loss), and developed the "harmonizing 13th party" of internal service and "yiyuan 13th party" of plaster therapy. Through systematic clinical observation and 11 multi-center, randomized, double-blind and controlled (RCT) clinical trials, the team demonstrated that the total clinical efficiency of TCM in the prevention and treatment of chronic skeletal diseases was over 90% and the recurrence rate was low. In addition, they founded the external treatment of "leveraging" (external imbalance bones and muscles) and "the physique balancing fuck" "spinal balance hold" "molisch's 12 YangShengGong" word "neck waist exercises" nine whole neck three-step method of "the whole waist three-step method" nine "three-step method" nine whole knee rich features and advantages of traditional Chinese medicine such as means of prevention and control of chronic disease of bones and muscles, curative effect is distinct, both at home and abroad has been widely used and promoted.

Follow the bi-directional conversion to do research

Traditional Chinese medicine has a long history and a long history. Professor wang yongjun introduced that in the application of Chinese medicine to prevent and cure chronic diseases, in addition to "knowing it as it is", now has entered the stage of "knowing it as it is". For example, in the study of osteoporosis, the team discovered new genes that regulate bone metabolism, and discovered that traditional Chinese medicine for kidney-nourishing and sperm filling can up-regulate Wnt/ hy-catenin-bmp and Notch signaling pathways and promote bone formation. It can up-regulate OPG/RANKL signal and inhibit bone loss. The research results in this field are generally recognized by the academic circle, and have won the first prize of Shanghai science and technology progress award in 2014 and the second prize of national science and technology progress award in 2015.

In addition, professor wang's team also found for the first time that intervertebral disks have the function of organs and present the basic law of aging. This study for the first time demonstrated the key regulatory roles of human-catenin and Smad3 in the process of disc degeneration, and found the molecular mechanism of prolonging qi and removing stasis to delay the disc degeneration.

"To inherit and develop the cause of traditional Chinese medicine, we should follow the idea and method of two-way transformation." professor wang yongjun explained that the researcher-initiated research should be originated from clinical practice. And through modern clinical trial research and basic research, we can explore the rules of TCM prevention and treatment of diseases, form new innovative results, nurture clinical practice, improve curative effect and even spread to the community, and truly realize the two-way transformation of "clinical -- experimental -- clinical and community".

Cultivate advanced compound talent should be early

Talent is the key to the inheritance and development of traditional Chinese medicine. At present, only master and doctoral students in traditional Chinese medicine have more opportunities to follow their tutors into the laboratory and carry out clinical practice. According to professor wang yongjun, Shanghai university of Chinese medicine implemented the multi-tutor system in advance in the undergraduate stage of 7-year students, and arranged a clinical experienced tutor to guide students in clinical practice, and a tutor familiar with modern life science to guide them to study basic research.

Yong-jun wang, says professor of Shanghai university of traditional Chinese medicine training talents of "six combinations" mode, namely the traditional Chinese medicine combined with western medicine, combining theory with clinical practice, combined with foreign language, the ancient medical Chinese medicine combined with biology, traditional culture and modern science and technology and business technology and organization and management, is worthy of reference for colleges and universities of Chinese medicine. For the development of traditional Chinese medicine, excellent leading talents and master talents are needed, and more importantly, a large number of senior inter-disciplinary talents need to be cultivated.